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AutoImmune Diseases and Chiropractic

Chiropractic is increasingly explored as a complementary approach for individuals with autoimmune conditions, emphasizing the role of the spine and nervous system in overall health. By addressing spinal function through adjustments, chiropractic care reduces stress on the body, supports efficient nervous system communication, and promotes mechanisms linked with pain modulation and inflammation regulation. Enhanced brain–body communication along the neuroimmune axis has been associated with improved adaptability and resilience, which may influence the frequency and intensity of symptom flare-ups. Case reports describe individuals with conditions such as lupus, Hashimoto’s, and rheumatoid arthritis noting improvements in comfort, function, and quality of life with consistent chiropractic care. While chiropractic does not claim to diagnose or treat autoimmune diseases, it may provide valuable support as a complementary strategy that works alongside the body’s natural processes.

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Chiropractic, the Nervous System, and Autoimmune Diseases

Autoimmune diseases develop when immune regulation fails and the immune system initiates sustained attacks against the body’s own tissues, producing chronic inflammation, progressive tissue injury, and functional impairment. Conditions such as Multiple Sclerosis, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Hashimoto’s thyroiditis, psoriasis, and inflammatory bowel diseases including Crohn’s disease and ulcerative colitis illustrate how immune dysregulation can affect the nervous system, joints, connective tissue, endocrine organs, and internal organs simultaneously. Individuals living with autoimmune disorders frequently experience pain, fatigue, neurological symptoms, and reduced quality of life. Chiropractic care, with its emphasis on optimizing nervous system function, offers a nonpharmacologic and supportive approach that may enhance physiological regulation in this population. By correcting spinal misalignments and reducing mechanical and neurological stress, chiropractic adjustments can decrease nociceptive input to the central nervous system, improve autonomic balance, and support neuroimmune communication. These mechanisms may contribute to reductions in pain and symptom burden while improving overall wellbeing acr.amegroups.org spinalresearch.com.au. This body of evidence highlights the relationship between spinal alignment, nervous system regulation, and immune function, and suggests that supporting neural integrity may help the body adapt more effectively even in chronic autoimmune conditions.

The Neurobiology of Autoimmune Disease and Chiropractic’s Role

Autoimmune diseases involve more than immune activity alone and are fundamentally linked to nervous system regulation. The brain, spinal cord, and peripheral nerves continuously modulate immune cell behavior through autonomic signaling, neuroendocrine pathways, and central integration of stress responses. When this bidirectional communication becomes disrupted by factors such as chronic psychological stress, physical trauma, or toxic exposures, immune regulation can become maladaptive, increasing the likelihood of persistent inflammation and autoimmune activity. Neural dysregulation alters cytokine signaling, immune cell trafficking, and inflammatory thresholds, which can contribute directly to disease initiation and progression. Understanding autoimmunity through this neurobiological framework highlights why restoring balanced nervous system function is relevant to immune stability and sets the foundation for examining the neurological mechanisms involved in autoimmune conditions.

Autonomic nervous system imbalance is frequently observed in individuals with autoimmune conditions, with heightened sympathetic activity and reduced parasympathetic tone contributing to immune dysregulation. Sustained sympathetic activation associated with chronic stress increases proinflammatory signaling and is linked to disease flares and symptom exacerbation. Chiropractic adjustments may influence autonomic balance by reducing mechanical and neurological stress on spinal and peripheral nerve pathways. Case based investigations have reported changes in immune markers following chiropractic care, including alterations in T lymphocyte and B lymphocyte counts, natural killer cell activity, antibody levels, and phagocytic function acr.amegroups.org. Restoration of balanced neural signaling may enhance parasympathetic activity mediated by the vagus nerve, which plays a central role in suppressing excessive inflammatory responses. Experimental and clinical research has described a cholinergic antiinflammatory pathway in which vagal efferent signaling modulates cytokine production by immune cells acr.amegroups.org. Upper cervical spinal adjustments have been proposed to influence this pathway through stimulation of cervical baroreceptors and associated reflex arcs that interact with vagal nuclei, thereby supporting antiinflammatory regulation acr.amegroups.org. Through these mechanisms, chiropractic care may reduce excessive stress related neural signaling while supporting neuroimmune communication that promotes immune stability and inflammatory control.

Cerebrospinal fluid flow and neuroimmune health are closely linked, as cerebrospinal fluid bathes the brain and spinal cord, facilitates nutrient delivery, and removes metabolic waste. When cerebrospinal fluid circulation is impeded, such as by structural misalignment in the upper cervical spine, intracranial pressure may increase and contribute to inflammation within neural tissues. Imaging research using upright magnetic resonance imaging in individuals with multiple sclerosis has demonstrated that misalignment of the upper cervical spine can obstruct normal cerebrospinal fluid flow blog.doppsne.com. These obstructions have been associated with abnormal leakage of cerebrospinal fluid into brain tissue and accumulation of proteins, which may provoke immune mediated attacks on nerve fibers blog.doppsne.com. In a 2011 imaging study, all examined multiple sclerosis patients exhibited significant cerebrospinal fluid flow restriction at the atlas level blog.doppsne.com. Notably, one patient in that study received a gentle upper cervical chiropractic correction, after which intracranial pressure was reduced and the abnormal cerebrospinal fluid leakage was dramatically decreased, coinciding with resolution of neurological symptoms including severe vertigo and balance disturbances blog.doppsne.com. Following correction of the atlas misalignment, the patient experienced marked reduction in multiple sclerosis related symptoms as more normalized cerebrospinal fluid dynamics were restored blog.doppsne.com. These findings support a mechanistic association between spinal alignment, cerebrospinal fluid circulation, and immune activity within the central nervous system, suggesting that chiropractic care may influence conditions such as multiple sclerosis by improving fluid dynamics and reducing mechanical stress on the brain and spinal cord.

Brain plasticity and cortical organization are directly influenced by the quality of sensory and motor input received from the body. Chronic pain, impaired posture, and restricted spinal motion alter afferent signaling to the central nervous system, which can degrade cortical mapping within sensory and motor regions of the brain. When spinal joint dysfunction disrupts proprioceptive input, corresponding cortical areas may become under engaged, reducing the efficiency with which the brain regulates motor output, autonomic activity, and immune signaling. Experimental research demonstrates that spinal adjustments measurably alter brain function. A 2016 study published in the journal Neural Plasticity reported that a single chiropractic adjustment produced approximately a 20 percent improvement in prefrontal cortex activity as measured by electroencephalography and related neurophysiological tests spinalresearch.com.au. The prefrontal cortex plays a central role in executive decision making, emotional regulation, autonomic control, immune modulation, and motor planning. The study authors concluded that spinal adjustment alters how the prefrontal cortex processes information, providing evidence that spinal function directly influences brain function spinalresearch.com.au. Additional investigations have shown that spinal adjustments increase brain to muscle drive by up to 45 percent as measured through H reflex and V wave responses, indicating enhanced efficiency of descending motor commands spinalresearch.com.au. These changes are relevant to autoimmune conditions because effective immune regulation depends on precise central nervous system control. By restoring spinal joint motion and improving proprioceptive signaling, chiropractic care supports more accurate cortical representation of the body, allowing the brain to regulate physiological systems with greater precision. Clinical reports of improved coordination, cognitive clarity, and reduced pain following adjustments are consistent with improved nervous system integration. Enhanced neural organization may reduce maladaptive signaling patterns that contribute to immune dysregulation, supporting a more balanced and controlled immune response.

In summary, chiropractic care does not resolve the underlying autoimmune pathology and appropriate medical management should continue, but it can address neurological and musculoskeletal contributors that exacerbate autoimmune activity. By correcting spinal misalignments, chiropractic adjustments reduce mechanical and sensory stress on the nervous system, improve cerebrospinal fluid circulation, and enhance communication between the brain and peripheral tissues. Improved neural signaling and fluid dynamics can contribute to reductions in pain, improved organ function, decreased inflammatory burden, and measurable improvements in daily function and quality of life for individuals with autoimmune disease. The following clinical case studies demonstrate how patients with a range of autoimmune conditions responded favorably to chiropractic care, with reported symptom relief and objective functional changes documented in peer reviewed journals and clinical reports. Collectively, these findings support the concept that improved nervous system regulation can meaningfully influence physiological resilience and recovery in autoimmune conditions.

Case Studies: Autoimmune Patients Finding Relief with Chiropractic

Chiropractic care for multiple sclerosis focuses on reducing mechanical and neurological stress on the spine in a condition where immune mediated processes damage the central nervous system and produce symptoms such as numbness, weakness, visual disturbance, fatigue, and balance impairment. Chiropractic care is not a curative intervention for multiple sclerosis, and appropriate medical management remains essential, but clinical reports indicate that many patients experience meaningful improvements in pain levels, joint mobility, and daily function when spinal dysfunction is addressed. In one documented case, a fifty one year old woman with a five year history of multiple sclerosis experienced a dramatic improvement in symptoms after initiating regular chiropractic care, reporting reduced pain, improved mobility, increased energy, enhanced lung capacity, and greater participation in daily activities within twelve visits cihfc.com. In another case, a fifty seven year old woman with multiple sclerosis received twenty four sessions of instrument assisted spinal adjustments using the Activator Technique over a two month period and demonstrated measurable improvements in both subjective and objective outcomes, including reduced numbness, improved balance, and enhanced visual function vertebralsubluxationresearch.com. The authors of that report concluded that the patient experienced positive health outcomes during chiropractic care and emphasized the need for further investigation into chiropractic interventions for individuals with multiple sclerosis vertebralsubluxationresearch.com. Collectively, these cases suggest that by improving spinal joint motion, enhancing nervous system regulation, and potentially supporting healthier cerebrospinal fluid dynamics, chiropractic care may contribute to improved functional capacity and quality of life in people living with multiple sclerosis.

Why early, multimodal recovery matters

Chiropractic care for systemic lupus erythematosus addresses neurological and musculoskeletal factors that may influence disease expression in a condition characterized by immune mediated inflammation affecting joints, skin, kidneys, and other organs. Systemic lupus erythematosus is generally regarded as incurable within conventional medical frameworks, with treatment focused on suppressing immune activity and managing disease flares. However, published chiropractic case reports describe notable clinical outcomes following targeted spinal care. One report documented a thirty four year old woman with active systemic lupus erythematosus who received specific chiropractic adjustments using the Pierce Results technique and experienced substantial symptom improvement after twelve visits, including eleven adjustments to the cervical and thoracic spine, accompanied by laboratory findings indicating complete remission of systemic lupus erythematosus vertebralsubluxationresearch.com. Chiropractic assessment in that case utilized infrared thermography and spinal radiography to identify and correct spinal dysfunction, and the patient’s medical physician confirmed that disease remission coincided with the period of chiropractic care vertebralsubluxationresearch.com. In a separate case, an eighteen year old woman with systemic lupus erythematosus and chronic neck and joint pain was advised to begin immunosuppressive therapy but instead underwent an intensive course of chiropractic care consisting of fifty six low force adjustments over seven days using a functional neurology approach. Following two concentrated treatment periods, the patient demonstrated sufficient clinical improvement that her medical physician reversed the diagnosis, concluding that she no longer met diagnostic criteria for systemic lupus erythematosus apcj.net. These cases do not establish chiropractic care as a cure for lupus, but they suggest that improving spinal function and nervous system regulation may influence immune activity, reduce pain and fatigue, decrease flare frequency, and significantly improve quality of life in some individuals with systemic lupus erythematosus.

Chiropractic care for rheumatoid arthritis addresses neurological and biomechanical contributors in an autoimmune condition characterized by chronic synovial inflammation, joint pain, stiffness, and progressive deformity. Conventional management primarily relies on immune suppressive medications, while chiropractic care is used as a complementary strategy to improve joint mechanics and reduce adverse neural input to affected tissues. A published case report in the Annals of Vertebral Subluxation Research followed a fifty four year old woman with severe long standing rheumatoid arthritis affecting her hands, feet, and knees who entered chiropractic care with constant pain rated as nine out of ten without medication and marked gait instability requiring support for ambulation vertebralsubluxationresearch.com. Following a comprehensive examination, a structured chiropractic care plan was initiated that included specific spinal adjustments and prescribed home exercises. Over four months, the patient experienced a substantial reduction in symptoms, and by ten months her pain had decreased to one out of ten without pharmacologic support, accompanied by restoration of functional abilities such as walking stairs, exercising, and dancing cihfc.com cihfc.com. The authors noted that after seven years of limited benefit from medication alone, improvements in spinal alignment and nervous system function coincided with sustained symptom reduction and discontinuation of pain medications vertebralsubluxationresearch.com. A second report described a twenty eight year old woman with rheumatoid arthritis who underwent corrective chiropractic care using the Pettibon Technique for three months and demonstrated improvements in pain, fatigue, and daily function, along with measurable changes in spinal alignment on follow up radiographic imaging vertebralsubluxationresearch.com. The patient reported a significant improvement in quality of life, mobility, and physical capacity during care vertebralsubluxationresearch.com. These reports suggest that improving spinal alignment and neural signaling through chiropractic adjustments may reduce nociceptive and inflammatory signaling to affected joints, contributing to decreased pain perception, improved movement, reduced reliance on analgesic medications, and enhanced participation in daily activities for some individuals with rheumatoid arthritis.

Chiropractic care for Crohn’s disease addresses neurological and autonomic factors in an autoimmune inflammatory bowel condition characterized by abdominal pain, diarrhea, and impaired nutrient absorption. The gastrointestinal tract contains an intrinsic enteric nervous system that communicates continuously with the spinal cord and brain, and autonomic nerve fibers supplying the intestines originate from thoracic and lumbar spinal segments. Chiropractic adjustments directed to these spinal regions may influence gastrointestinal function by improving autonomic signaling to the bowel and reducing maladaptive stress related neural input. A published case report documented complete remission of Crohn’s disease in a sixty year old male who had experienced six years of persistent symptoms including hourly diarrhea, abdominal cramping, chronic illness sensation, and markedly reduced quality of life despite multiple medications vertebralsubluxationresearch.com. After initiating regular full spine diversified chiropractic adjustments, the patient reported immediate symptom relief following the first two visits, followed by progressive improvement leading to full resolution of Crohn’s related symptoms over the course of care vertebralsubluxationresearch.com. After nine months, the patient’s gastroenterology specialist confirmed sustained clinical remission, and the treating chiropractor noted normalization of digestive function and gut flora, which was attributed to improved nervous system regulation combined with dietary support vertebralsubluxationresearch.com. Beyond individual cases, a clinical study published in two thousand seven reported that twelve of seventeen Crohn’s disease patients who received spinal adjustments achieved long term stable remission of symptoms commonwealthchiro.com. The investigators observed a high prevalence of vertebral subluxations in this population and proposed that correction of spinal dysfunction may reduce neurogenic contributions to intestinal inflammation commonwealthchiro.com. An additional case report described a thirty two year old female with chronic inflammatory bowel disease who experienced complete resolution of symptoms following chiropractic care commonwealthchiro.com. Collectively, these reports suggest that restoring spinal and autonomic nervous system function may contribute to improved intestinal regulation, reduced inflammatory activity, fewer disease flare ups, improved digestion, and meaningful gains in quality of life for some individuals living with Crohn’s disease.

Chiropractic care for Hashimoto’s hypothyroidism addresses neurological and neuroendocrine factors involved in autoimmune thyroid dysfunction, which commonly presents with fatigue, weight gain, cold intolerance, and reduced metabolic activity due to impaired thyroid hormone regulation. Thyroid function is governed by central nervous system control through hypothalamic and pituitary signaling, and cervical spinal afferent input contributes to autonomic and neuroimmune regulation of endocrine organs. A published case study utilizing Torque Release Technique described a sixty one year old woman with long standing Hashimoto’s hypothyroidism who experienced persistent fatigue, weight gain, migraines, dizziness, tinnitus, and symptoms consistent with Meniere’s disease despite ongoing medical management wellnessistheway.net. Chiropractic evaluation identified significant spinal dysfunction and muscular hypertonicity in the cervical spine, thoracic spine, lumbar spine, and pelvis, regions associated with autonomic and neuroendocrine signaling pathways wellnessistheway.net. Following a structured course of gentle chiropractic adjustments, the patient demonstrated substantial clinical improvement including increased energy, progressive weight loss, reduction in vertigo and tinnitus episodes, and improved functional capacity. Most notably, laboratory testing confirmed normalization of thyroid hormone levels, indicating resolution of hypothyroidism while under chiropractic care wellnessistheway.net. This case supports the concept that improving spinal and nervous system function may reduce maladaptive neural stress on hypothalamic pituitary thyroid regulation and immune signaling, thereby allowing restoration of endocrine balance in select individuals with autoimmune thyroid disease.

Chiropractic care for Psoriasis and Psoriatic Arthritis: Psoriasis is an autoimmune condition characterized by dysregulated immune activity that accelerates keratinocyte proliferation, producing erythematous, scaly skin lesions and, in some individuals, inflammatory joint involvement consistent with psoriatic arthritis. Although clinically expressed in the skin and joints, psoriasis is increasingly understood as a systemic inflammatory disorder influenced by neuroimmune regulation and chronic stress. A published case report from 2011 described an 85 year old male with long standing, severe psoriasis affecting nearly his entire body who underwent chiropractic care using the Toftness System, a low force technique designed to reduce spinal nerve interference vertebralsubluxationresearch.com. Over a four month period involving 30 visits, the chiropractor addressed documented spinal subluxations, particularly in regions associated with autonomic and immune regulation vertebralsubluxationresearch.com. The patient demonstrated marked and progressive improvement, with substantial regression of psoriatic plaques, reduced pruritus, and decreased skin irritation by the conclusion of care. The authors reported a clear positive clinical response to chiropractic intervention, concluding that spinal adjustments were temporally associated with meaningful improvement in psoriasis severity vertebralsubluxationresearch.com. Additional case observations have reported similar outcomes, supporting the hypothesis that improving spinal and nervous system function may reduce neurogenic stress signaling and downstream pro inflammatory cytokine activity that contributes to psoriasis flares. Patients frequently report that improved spinal alignment and reduced physiological stress correlate with decreased pain and fewer exacerbations, whereas heightened stress and postural strain previously preceded symptom recurrence. These findings support a neuroimmune model in which optimizing spinal and nervous system function may positively influence systemic inflammatory skin conditions.

Chiropractic care for Myasthenia Gravis (MG): Myasthenia gravis is a rare autoimmune neuromuscular disorder in which the immune system targets acetylcholine receptors at the neuromuscular junction, resulting in impaired signal transmission between nerves and muscles and causing fluctuating muscle weakness and fatigue. Ocular muscles are commonly affected, producing ptosis and diplopia, and the condition can progress to generalized weakness involving limb and respiratory muscles. Conventional management focuses on medications that enhance acetylcholine availability or suppress immune activity. Emerging case literature suggests that chiropractic care may influence neurological regulation in select patients. A published case report from 2019 described a 51 year old female with confirmed myasthenia gravis who initially sought chiropractic care for cervical and lumbar pain but subsequently experienced resolution of her myasthenic symptoms acr.amegroups.org. The diagnosis had been established through elevated autoantibody levels and objective muscle weakness, and the patient had discontinued standard medications due to adverse effects with progressive clinical decline acr.amegroups.org. Chiropractic care consisted of spinal adjustments addressing dysfunction in the cervical and lumbar regions using a diversified manual technique. Within one week of initiating care, the patient reported measurable improvement in limb strength acr.amegroups.org. After one month, her double vision resolved and full muscle strength returned, consistent with clinical remission of myasthenia gravis acr.amegroups.org. She continued with periodic maintenance care and remained symptom free at eight month follow up acr.amegroups.org. The authors proposed plausible neurobiological mechanisms including reduced sympathetic stress, improved central nervous system regulation, and modulation of cholinergic signaling pathways. Prior reports, including work by Alcantara and colleagues, have described similar improvements in myasthenia gravis patients following cervical spine chiropractic adjustments, supporting the possibility of a reproducible association acr.amegroups.org. The close temporal relationship between spinal care and neurological improvement suggests that optimizing spinal and autonomic function may enhance neuromuscular communication and influence immune mediated dysfunction in selected individuals with myasthenia gravis.

Each of the cases described demonstrates the potential clinical relevance of a holistic approach that prioritizes nervous system regulation in the management of autoimmune disease. Across conditions including multiple sclerosis, systemic lupus erythematosus, inflammatory bowel disease, and inflammatory joint disorders, chiropractic care has been associated with reductions in pain, improvements in functional capacity, and meaningful gains in daily activity for individual patients. These reports represent documented case level observations rather than universal outcomes, and chiropractic care is most appropriate when integrated with ongoing medical evaluation and management. The cases collectively suggest that addressing contributory factors such as spinal joint dysfunction, altered posture, chronic mechanical stress, and sustained autonomic imbalance may reduce physiological strain that exacerbates autoimmune activity. By improving spinal mechanics and neural signaling, chiropractic care may help modify disease burden and support functional recovery in select patients within a coordinated healthcare framework.

Why Chiropractic Could Improve Your Life with Autoimmune Disease

If you are living with an autoimmune disorder, persistent symptoms despite medications, dietary changes, and supplements often reflect deeper dysregulation rather than isolated immune malfunction. Chiropractic care offers a distinct approach by focusing on optimizing nervous system function rather than directly suppressing immune activity. The brain and spinal cord regulate immune behavior through continuous neural signaling that influences organ function, inflammatory responses, and immune cell activity. When spinal joint dysfunction, chronic nociceptive input, or altered biomechanics disrupt this signaling, neural communication becomes distorted and immune responses can become exaggerated or poorly regulated. By correcting spinal dysfunction and reducing abnormal mechanical and sensory stress on the nervous system, chiropractic care aims to restore clearer neural signaling between the brain and peripheral tissues. Improved neural communication supports more appropriate immune regulation, allowing physiological systems to respond with greater precision and resilience rather than persistent inflammatory overactivation.

The outcomes documented in the preceding case studies demonstrate that individuals with autoimmune conditions frequently experience meaningful improvements in function and daily well being, even when those conditions have been considered chronic or permanent. Quality of life encompasses functional capacity, pain levels, cognitive clarity, sleep quality, energy, and the ability to engage in normal activities, not laboratory values alone. Chiropractic care has repeatedly been associated with improvements in these domains by supporting more efficient nervous system regulation, which influences musculoskeletal function, autonomic balance, and immune signaling. A growing body of academic literature is now examining mechanisms long observed in clinical practice, namely that improved spinal alignment and reduced mechanical and neurological stress are associated with improved physiological regulation and tissue recovery. Chiropractic care is non invasive and emphasizes whole person assessment rather than isolated symptom suppression. When integrated appropriately alongside conventional medical management, chiropractic evaluation of spinal and nervous system function can identify contributing biomechanical and neurological factors that may influence autoimmune symptom severity. Given the complexity and multifactorial nature of autoimmune disease, a comprehensive approach that includes nervous system optimization may enhance functional outcomes and overall quality of life.

Stevens K. et al. (2017). Annals of Vertebral Subluxation Research: MS patient improved with Activator method – 24 sessions over 2 months yielded subjective & objective health improvementsvertebralsubluxationresearch.com.
Harden J. et al. (2017). Annals of VSR: Lupus patient’s symptoms “much improved” after 11 adjustments; follow-up blood work showed resolution of SLEvertebralsubluxationresearch.com.
Kolterman S. et al. (2019). Asia-Pac Chiropr J: 18-year-old with lupus received concentrated chiropractic care; medical diagnosis of lupus was reversed after care, indicating remissionapcj.net.
Brown D. & Korten J. (2023). Annals of VSR: 28-year-old with RA had 3 months of Pettibon spinal corrections; showed better spinal alignment, less pain, and “significant improvement in quality of life”vertebralsubluxationresearch.comvertebralsubluxationresearch.com.
“RA Helped with Chiropractic – Case Study.” Annals of VSR (2012): 54-year-old RA patient off all meds after 4 months; pain 9→1/10 in 10 months, regained ability to exercise and live normallycihfc.com.
Phillips M. & Wilt T. (2018). Annals of VSR: 60-year-old male with Crohn’s disease had complete remission after 9 months of chiropractic adjustments (plus diet); was able to stop all medicationsvertebralsubluxationresearch.comvertebralsubluxationresearch.com.
Seymour T. (2024). Commonwealth Chiro Blog: Cites 2007 study – 12 of 17 Crohn’s patients achieved long-term remission with spinal adjustments; vertebral subluxations were a common finding in Crohn’scommonwealthchiro.com. Also notes Blum’s 2003 case of a woman’s chronic IBD resolved following chiropracticcommonwealthchiro.com.
Wallis D. & Cuviello V. (2020). Annals of VSR: 61-year-old female with Hashimoto’s hypothyroidism saw hypothyroid resolution confirmed by lab tests after Torque Release Technique adjustments; symptoms like fatigue, weight gain, tinnitus greatly improvedwellnessistheway.net.
Tsuji Y. (2011). Annals of VSR: 85-year-old with body-wide psoriasis underwent 30 Toftness chiropractic sessions in 4 months; significant skin clearing observed, indicating a positive effect of chiropractic on this immune-mediated skin diseasevertebralsubluxationresearch.com.
Alcantara J. et al. (2018). Annals of VSR: Case of 38-year-old with advanced ankylosing spondylitis – gentle instrument and manual adjustments over 1 year led to improved posture, range of motion, and less pain; authors conclude chiropractic shows promise for AS patientsspinalresearch.com.auspinalresearch.com.au.
Chu E. & Bellin D. (2019). AME Case Reports: 51-year-old woman with Myasthenia Gravis had complete remission of MG symptoms within 1 month of starting cervical chiropractic adjustments; remained symptom-free and off medication at 8-month follow-upacr.amegroups.orgacr.amegroups.org. Authors discuss how vagal nerve modulation and improved acetylcholine signaling due to spinal alignment might explain this recoveryacr.amegroups.orgacr.amegroups.org.
Damadian R. & Chu D. (2011). Physiol Chem Phys & Med NMR: Study using upright MRI on MS patients found atlas misalignments causing CSF flow blockages in all patients; post-correction by an upper cervical chiropractor (Dr. Scott Rosa) showed restored CSF flow and cessation of MS vertigo/balance symptoms in the treated caseblog.doppsne.comblog.doppsne.com. This suggests upper cervical adjustments can reduce intracranial pressure and immune-triggering protein leaks in neuro-autoimmune conditions.